COMPARATIVE PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION OF BRANDED AND GENERIC FORMULATIONS OF MELOXICAM IN HEALTHY MALE VOLUNTEERS

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

Mario Del Tacca,1,2 Giuseppe Pasqualetti,3 Giovanni Gori,1 Pasquale Pepe,1 Antonello Di Paolo,2 Marianna Lastella,2 Ferdinando De Negri,1 Corrado Blandizzi2 1Clinical Pharmacology Centre for Drug Experimentation, Pisa University Hospital, 2Department of Clinical and Experimental Medicine, 3Geriatrics Unit, University of Pisa, Pisa, Italy Purpose: T

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Identification of the mechanisms responsible for anomalies in the tropical lower thermosphere/ionosphere caused by the January 2009 sudden stratospheric warming

We apply the Entire Atmosphere GLobal (EAGLE) model to investigate the upper atmosphere response to the January 2009 sudden stratospheric warming (SSW) event.The model successfully reproduces neutral temperature and total electron content (TEC) observations.Using both model and observational data, we identify a cooling in the tropical lower thermos

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